Book Hotels in Upstate South Carolina, SC
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Top Upstate South Carolina hotels

Cambria Hotel Greenville
135 Carolina Point Parkway, Greenville, SC
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $158 total per night from Jun 8 to Jun 9
$158 total
Jun 8 - Jun 9
Total includes taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
"Really nice hotel with friendly staff and amenities. Really clean and spacious rooms. The pool was really clean and nice. There was a nice bar in the lobby so thats aways a plus! It was also located in a perfect location. Close to everything. Would definitely recommend to friends and family."
Reviewed on May 29, 2025

Best Western Plus Greenville I-385 Inn & Suites
831 Congaree Rd, Greenville, SC
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $115 total per night from Jun 3 to Jun 4
$115 total
Jun 3 - Jun 4
Total includes taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Breakfast was average at best. Coffee was very good"
Reviewed on May 28, 2025

Hyatt Regency Greenville
220 N Main St, Greenville, SC
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $144 total per night from Jun 30 to Jul 1
$144 total
Jun 30 - Jul 1
Total includes taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"Was a wonderful stay. Staff was so friendly and such a perfect location. We'll be back for sure!"
Reviewed on May 31, 2025

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
851 Congaree Rd, Greenville, SC
Fully refundable
$107 nightly
The price is $118 total per night from Jun 29 to Jun 30
$118 total
Jun 29 - Jun 30
Total includes taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"Nice place"
Reviewed on May 27, 2025

Hilton Greenville
45 W Orchard Park Dr, Greenville, SC
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $134 total per night from Jun 29 to Jun 30
$134 total
Jun 29 - Jun 30
Total includes taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 18 conference rooms, free WiFi in public areas, ...
"Sure was nice"
Reviewed on May 26, 2025

Comfort Inn Greenville - Haywood Mall
246 Congaree Road, Greenville, SC
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $105 total per night from Jun 11 to Jun 12
$105 total
Jun 11 - Jun 12
Total includes taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"The stay was adequate for the price i paid"
Reviewed on May 28, 2025

Hyatt Place Greenville/Haywood
40 W Orchard Park Dr, Greenville, SC
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $111 total per night from Jul 1 to Jul 2
$111 total
Jul 1 - Jul 2
Total includes taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
"We were there for the week as my mother was in Hospice, and then back with family for the funeral. The woman who works nights ( I forget her name ) was wonderful and helped us out tremendously. I really appreciate her additional effort."
Reviewed on May 26, 2025

La Quinta Inn & Suites by Wyndham Greenville Haywood
65 W Orchard Park Dr, Greenville, SC
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $77 total per night from Jun 2 to Jun 3
$77 total
Jun 2 - Jun 3
Total includes taxes and fees
This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. ...
"Everything was perfect great area"
Reviewed on May 28, 2025

Days Inn by Wyndham Anderson
1007 George Smith Mill Rd, Anderson, SC
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $65 total per night from Jun 2 to Jun 3
$65 total
Jun 2 - Jun 3
Total includes taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"It was fine stay and safe"
Reviewed on May 30, 2025
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Upstate South Carolina with star-rating
Check Upstate South Carolina Hotels by Star Rating

4 Star Hotels
14 properties
Recent Upstate South Carolina hotel reviews by fellow wanderers

Hyatt Regency Greenville
5 out of 5
Posted 8 hours ago
Travelocity Verified Review
"Was a wonderful stay. Staff was so friendly and such a perfect location. We'll be back for sure! "
A verified traveler stayed at Hyatt Regency Greenville
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