Book Hotels in Upstate South Carolina, SC
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Top Upstate South Carolina hotels
Grand Bohemian Lodge Greenville, Autograph Collection
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
$401 nightly
The price is $441 total per night from Sep 27 to Sep 28
$441 total
Sep 27 - Sep 28
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
"Room was not ready. Check in said 4:00 but we had to wait a long time and they couldn’t tell us when our room would be ready."
Reviewed on Sep 12, 2026
Mint House Greenville Downtown by Kasa
101 Falls Park Dr Greenville SC
$115 nightly
The price is $127 total per night from Sep 27 to Sep 28
$127 total
Sep 27 - Sep 28
Total with taxes and fees
A 24-hour gym, self parking, and laundry facilities are featured at this apartment. Express check-in and express check-out are also provided.
"Great amenities and nearby attractions. Parking was confusing at first and somewhat doesn't make any sense."
Reviewed on Sep 21, 2026
Best Western Plus Greenville I-385 Inn & Suites
831 Congaree Rd Greenville SC
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $84 total per night from Oct 4 to Oct 5
$84 total
Oct 4 - Oct 5
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"I had to ask for towels. I asked for toilet paper and got half a used roll of toilet paper. Just two specific examples."
Reviewed on Sep 21, 2026
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
851 Congaree Rd Greenville SC
$99 nightly
The price is $110 total per night from Oct 19 to Oct 20
$110 total
Oct 19 - Oct 20
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"Nice hotel"
Reviewed on Sep 21, 2026
Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
$101 nightly
The price is $112 total per night from Sep 24 to Sep 25
$112 total
Sep 24 - Sep 25
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"Not the worst hotel but definitely don’t expect much."
Reviewed on Sep 21, 2026
Embassy Suites Greenville Golf Resort & Conference Center
670 Verdae Blvd Greenville SC
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $120 total per night from Oct 4 to Oct 5
$120 total
Oct 4 - Oct 5
Total with taxes and fees
A golf course, a 24-hour gym, and a restaurant are all featured at this resort. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Hilton Greenville
45 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$117 nightly
The price is $129 total per night from Oct 11 to Oct 12
$129 total
Oct 11 - Oct 12
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 18 conference rooms, free WiFi in public areas, ...
Hyatt Place Greenville/Haywood
40 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $91 total per night from Oct 18 to Oct 19
$91 total
Oct 18 - Oct 19
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Hotel Hartness
120 Halston Avenue Greenville SC
Fully refundableReserve now, pay when you stay
$208 nightly
The price is $228 total per night from Oct 4 to Oct 5
$228 total
Oct 4 - Oct 5
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the seasonal outdoor pool and perks like free self parking. ...
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See all available properties in Upstate South Carolina
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Upstate South Carolina with star-rating
Check Upstate South Carolina Hotels by Star Rating
4 Star Hotels
33 properties
Recent Upstate South Carolina hotel reviews by fellow wanderers
Mint House Greenville Downtown by Kasa
5 out of 5
Posted 8 hours ago
Travelocity Verified Review
"Great amenities and nearby attractions. Parking was confusing at first and somewhat doesn't make any sense."
A verified traveler stayed at Mint House Greenville Downtown by Kasa
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