Book Hotels in Upstate South Carolina, SC
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Top Upstate South Carolina hotels

Grand Bohemian Lodge Greenville, Autograph Collection
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
$332 nightly
The price is $364 total per night from Mar 24 to Mar 25
$364 total
Mar 24 - Mar 25
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Relax with a drink at the bar/lounge and enjoy perks like free ...
Perfectly located to walk to the river, downtown and peace center. Gorgeous asthetic, and pristine rooms, we loved the restaurant also! Staff we courteous and helpful in everyway. 10/10
Reviewed on Mar 2, 2026

Hyatt Place Greenville Downtown
128 East Broad Street Greenville SC
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $153 total per night from Mar 15 to Mar 16
$153 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Great location, clean and polite staff
Reviewed on Mar 1, 2026

Embassy Suites Greenville Golf Resort & Conference Center
670 Verdae Blvd Greenville SC
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $128 total per night from Mar 15 to Mar 16
$128 total
Mar 15 - Mar 16
Total with taxes and fees
A golf course, a 24-hour gym, and a restaurant are all featured at this resort. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
The staff at this hotel was super friendly and the room was great! We really enjoyed the breakfast and happy hour! Overall, I would highly recommend this hotel!
Reviewed on Mar 3, 2026

Hyatt Regency Greenville
220 N Main St Greenville SC
$149 nightly
The price is $163 total per night from Mar 22 to Mar 23
$163 total
Mar 22 - Mar 23
Total with taxes and fees
This smoke-free hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Great room, good price, nice staff.
Reviewed on Mar 1, 2026

Courtyard by Marriott Greenville Haywood Mall
70 Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $110 total per night from Mar 15 to Mar 16
$110 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
The motel as a whole was very clean and well maintained. The staff was excellent and very helpful. I would highly recommend if you are looking for a great place to stay for a reasonable price.
Reviewed on Mar 2, 2026

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
851 Congaree Rd Greenville SC
Fully refundable
$101 nightly
The price is $111 total per night from Mar 15 to Mar 16
$111 total
Mar 15 - Mar 16
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
The overall cleanliness of my room was subpar. There was hair, caked up dust and trash in my bathroom. The tub was very slippery, myself and grandchildren slipped several times while bathing. Several chips were under and behind the chair by the bed. The room felt pretty crowded for it to be for 4 ...
Reviewed on Mar 2, 2026

Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $101 total per night from Mar 5 to Mar 6
$101 total
Mar 5 - Mar 6
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
The room was very clean, it was a room with a king bed and a sofa bed plus a microwave, mini fridge, coffee machine. The reception desk was very helpful when I had to do a late check in.
Reviewed on Mar 1, 2026

Hyatt Place Greenville/Haywood
40 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $107 total per night from Mar 23 to Mar 24
$107 total
Mar 23 - Mar 24
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Great
Reviewed on Mar 3, 2026

Hilton Greenville
45 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $109 total per night from Mar 15 to Mar 16
$109 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 18 conference rooms, free WiFi in public areas, ...
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Hotels in Upstate South Carolina with star-rating
Check Upstate South Carolina Hotels by Star Rating

4 Star Hotels
11 properties
Recent Upstate South Carolina hotel reviews by fellow wanderers

Hyatt Place Greenville/Haywood
5 out of 5
Posted 2 hours ago
Travelocity Verified Review
"Great "
A verified traveler stayed at Hyatt Place Greenville/Haywood
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